Before taking Leflunomide, tell your doctor if you are allergic to Leflunomide or any other drugs.
Tell your doctor what prescription and nonprescription medications you are taking, especially cholestyramine (Cholybar, Questran), colestipol (Colestid), felbamate (Felbatol), mercaptopurine (Purinethol), rifampin (Rifadin, Rimactane, Rifater), methotrexate (Rheumatrex), tolbutamide (Orinase), troglitazone (Rezulin), and vitamins.
Tell your doctor if you have or have ever had liver or kidney disease, hepatitis, severe infections, or conditions affecting the bone marrow or the immune system (including human immunodeficiency virus [HIV] and acquired immunodeficiency syndrome [AIDS]).
Tell your doctor if you are breast-feeding.
If you are planning to father a child, you should talk to your doctor about stopping Leflunomide prior to conception.
You should not receive any vaccinations while taking Leflunomide unless you have talked with your doctor.
You should know that there is a special treatment for removing Leflunomide from your body once you stop taking it.
Ask your doctor for more information about this treatment.